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Treating Cyclical Anxiety/depression
A myPCOSteam Member asked a question 💭

I have what feels like PMDD symptoms each month and I'm trying to find the best way to treat it. I'm currently on 20mg Fluoxetine daily and not liking the side effects. Though I wasn't having side effects, 10mg wasn't cutting it for the extreme mood shift. Like clockwork, 5 days before my period it's like a switch and I'm hit with sudden anxiety which then fuels a level of depression. It seems to peak on day 3 of my period then goes by end of day 4 as quick as it came. I'm not currently taking… read more

posted December 26, 2018
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A myPCOSteam Member

I will say I had Vitamin D deficiency for years. My lowest level was 16 and now it's 50s. I feel like my mood swings are better. When I start to feel annoyed I seem to recognize it earlier. So, I would at least get it checked and if it's low your doctor can recommend the right dosage to help it improve😊

posted December 27, 2018
A myPCOSteam Member

Yes. Studies are still being conducted and its a bit inconclusive at this time - but the studies suggest that vitamin D could play a role. So, in my opinion its worth looking into. Here's an excerpt from the National Library of Medicine, study done in 2009

"Premenstrual Syndrome and Premenstrual Dysphoric Disorder
PMS is a disorder characterized by moderate to severe physical and emotional symptoms in the luteal phase of the menstrual cycle that substantially interfere with normal life activities and interpersonal relationships.59,60 Some of the most common emotional symptoms are depression, irritability, mood swings, and anxiety.61–63 Women in whom affective symptoms predominate may also meet criteria for PMDD, a more severe form of PMS that is associated with significant impairment of normal functioning.6,63 PMDD is recognized as a mood disorder in the DSM-IV.6

A small body of research suggests that circulating levels of vitamin D, calcium and PTH may be involved in the development of menstrual symptoms, PMS and PMDD. It has been suggested that women with luteal phase symptoms consistent with PMS may be experiencing vitamin D deficiency, calcium dysregulation, and hyperparathyroidism.64 A small number of studies have explored the relationship between these vitamin D related biomarkers and menstrual symptoms. Thys-Jacobs et al. (1995)65 reported significant differences in levels of these biomarkers in 7 PMS cases compared to 5 symptom-free controls. 1,25(OH)2D and PTH were higher in PMS cases than controls in the follicular, ovulatory and luteal phases of the menstrual cycle, while 25(OH)D levels were significantly lower at all phases. However, a second recent study by the same investigators reported that mean serum levels of 25(OH)D and 1,25(OH)2D were similar in women with 68 PMDD and 47 healthy control women.66

Vitamin D supplementation for the prevention or treatment of PMS has not been explored directly. However, low dietary vitamin D intake has also been associated with the initial development of PMS. A study by Bertone-Johnson et al. (2005)67 in a subset of the Nurses’ Health Study II cohort found that women with the highest reported intake of vitamin D from food sources, equivalent to approximately 400 IU per day, had a significant 41% lower risk of developing PMS over the next 2–4 years compared to women with the lowest intake (P for trend = 0.01). Additional evidence concerning the role of vitamin D deficiency in PMS/PMDD is clearly needed."

source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC29...

posted December 27, 2018
A myPCOSteam Member

Not to say this would be a cure-all, but have you had your vitamin D levels checked?

posted December 27, 2018
A myPCOSteam Member

Thank you!!

posted December 27, 2018
A myPCOSteam Member

I have not had them checked. Could that impact mood?

posted December 27, 2018

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