I have been having highs and lows because I haven't stepped. High dheas can cause insomnia or sleep issues and anxiety.

Hi, I am also on metformin. I find metformin helped in the beginning but if you are not consistent with the medication it may not help.

I’m also on metformin and yaz. It helped in the beginning but now worry I have built resilience to metformin as well!

I have been on Lexapro for bipolar before. It was one of the best ones I ever had, but they tried to switch me to celexa since they're "similar"& it was cheaper... Did NOT do so well. I've known other ppl who've taken metformin. One person was given it for weight loss, but it ended up causing them reliance for the insulin regulation after a while. I was only ever on birth control once and it was the DEPO shot. I don't remember it helping, but I did get out on progesterone that I would take for so many days each month to regulate, and I think it was starting to help... I'm sorry I've worked with lots of Drs but never really go to them so I don't have more experience to help. Good luck!