Provera (medroxyprogesterone) is a progestin therapy that can be used to help trigger a period in people with PCOS. It works by supplementing progesterone, which signals the uterine lining to shed. This helps protect the uterus and lowers the risk of endometrial hyperplasia (thickening of the uterine lining).
Progestin Show Full Answer
Provera (medroxyprogesterone) is a progestin therapy that can be used to help trigger a period in people with PCOS. It works by supplementing progesterone, which signals the uterine lining to shed. This helps protect the uterus and lowers the risk of endometrial hyperplasia (thickening of the uterine lining).
Progestin therapy options include:
- Provera pills (medroxyprogesterone)
- Medroxyprogesterone injections (Depo-Provera)
- Hormonal IUDs like Mirena If Provera doesn't work to induce a period, there are other options worth discussing with a healthcare provider. These may include:
- Combination birth control pills — containing estrogen and progestin to regulate cycles and lower androgen levels
- Metformin — helps improve insulin sensitivity, which can lower androgens and encourage ovulation and more regular cycles
- Lifestyle changes — even a 5–10% reduction in body weight can help restore ovulation and regulate periods
- GLP-1 medications — newer options that may improve insulin response and support more regular cycles
It's worth noting that Provera doesn't address symptoms like acne or unwanted hair growth, so if those are concerns too, combination birth control pills may be a better fit.
Always loop in a healthcare provider before switching or adding treatments — what works varies from person to person with PCOS.
AI-generated responses are not a substitute for medical advice. These services are not intended to
diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.
9 PCOS Treatment Options
September 6
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